Project A01

Amplified formulas.

Attuned to skin.

Amplified formulas.

Attuned to skin.

Vision

My intention with Project A01 is to design evidence-driven, high-performance skincare formulas, guided by a commitment to function over flourish, and scientific rigour over excess. This means questioning the defaults, the shortcuts, the "good enough”. Not for complexity's sake, but to care better. To create from intention, not impulse. In an era of surface solutions and fleeting trends, innovation begins with perspective, questioning, and bridging. And where evidence meets imagination, overlooked synergies become new opportunities.

Vision

My intention with Project A01 is to design evidence-driven, high-performance skincare formulas, guided by a commitment to function over flourish, and scientific rigour over excess. This means questioning the defaults, the shortcuts, the "good enough”. Not for complexity's sake, but to care better. To create from intention, not impulse. In an era of surface solutions and fleeting trends, innovation begins with perspective, questioning, and bridging. And where evidence meets imagination, overlooked synergies become new opportunities.

Comprehensive biomimetic formulations.

Designed to support the skin's natural ability to protect, repair, and adapt.

Comprehensive biomimetic formulations.

Designed to support the skin's natural ability to protect, repair, and adapt.

Formulating philosophy

Each formula takes form at the intersection of established evidence and emerging insight, guided by a clear intention to support the skin’s natural function through purposeful, streamlined care.

Scientific validation 

Ingredients are selected for their relevance to skin function, prioritising proven efficacy and understood mechanisms over trends.

Precision & Purity

High-purity bioactives are enhanced through thoughtful delivery approaches and used at evidence-based concentrations to ensure both performance and skin compatibility.

Bioadaptive Formulations

Skin functions as a responsive, self-regulating ecosystem, continuously adapting to environmental flux, oxidative challenges, and internal cycles. Our formulations are crafted to align with these intricate processes, employing biomimetic principles that support and enhance the skin's natural ability for protection an repair, .

A restrained ingredient selection.

Each ingredient is evaluated against stringent criteria: purity of the raw material, biological relevance, bioavailability, mechanism of action, and strength of supporting evidence. This process ensures not only functional integrity, but also reproducible results and consistent efficacy across every product.

Engineered for bioavailability.

The skin barrier naturally restricts the penetration of substances, limiting many promising molecules from reaching viable skin layers.

Bridging high-potency actives with advanced delivery science, we have developed custom encapsulation systems engineered to optimize stability, dermal penetration, and bioavailability, delivering selected compounds to the deeper layers where they can perform most effectively.

Principles applied

This inaugural formulation responds to the complex challenges of accelerated skin stressors. Moving beyond surface intervention, it emphasizes deep functional support, to enhance the skin's innate capacity to protect, repair, and sustain long-term health.

Serum F-01

BA01 is a foundational serum designed to reinforce the skin’s natural defence and repair systems.

Going beyond protection, it supplements the skin with highly pure compounds selected for their ability to strengthen endogenous antioxidant and reparative pathways. Delivered through a proprietary liposomal complex optimised for penetration and bioavailability, these actives help regulate oxidative stress and inflammatory responses triggered by UV exposure and environmental stressors—supporting dermal structural integrity and visibly improving tone, radiance, and texture.

Formulated as a biomimetic emulsion using skin-identical phospholipids, BA01 supports barrier integrity and hydration, creating conditions for sustained equilibrium and healthy function.

Formulation

Proprietary

Liposomal Complex

A proprietary liposomal encapsulation complex developed to optimise the delivery of bioactive antioxidant compounds into the deeper layers of the epidermis. These molecules are known not only for their strong radical scavenging capacity but also for their documented ability to positively modulate biological pathways involved in endogenous antioxidant defences, regulate the oxidative chain reactions, control the inflammatory cascade triggered by UV exposure and environmental stressors, and control the melanogenesis process leading to hyperpigmentation.

Flavonoid (≥95%)

Flavonoid (≥95%)

Astaxanthin (≥95%)

Enhanced Skin Deposition

1x

1x

Encapsulated compounds

Free compounds (non-encapsulated)

Results from internal testing using Franz cell diffusion and fluorescence confocal microscopy, demonstrating delivery of encapsulated compounds to the basal epidermis.

Enhanced Skin Deposition

1x

1x

Encapsulated compounds

Free compounds (non-encapsulated)

Results from internal testing using Franz cell diffusion and fluorescence confocal microscopy, demonstrating delivery of encapsulated compounds to the basal epidermis.

DNA Repair Enzyme

Photolyase is a light-activated enzyme known to support the skin’s natural repair response to UV-induced DNA alterations. By contributing to the correction of visible signs of photodamage, it helps maintain skin integrity over time.

Biomimetic peptides

Biomimetic peptides selected for their role in maintaining skin structure, supporting both proactive and reparative actions.

Hydration Support

A network of humectants and biomimetic phospholipids helps maintain optimal hydration dynamics, supports barrier function, and contributes to skin comfort and suppleness across varying environmental conditions.

Be part of it

Join the list to follow the project’s development and access pilot testing first.

©2025 André Duarte

11:42

©2025 André Duarte