Project A01

Amplified skincare

designed for performance.

Amplified skincare

designed for performance.

Vision

Project A001 began as a quiet inquiry into what skin truly needs—not to mask, but to support. Our work centers on bioadaptive formulations that respect the skin’s complex biology, designed to deliver meaningful actives through advanced systems that prioritise long-term resilience over short-term promises. Fewer formulas, thoughtfully composed to optimise skin function over time.designed for performance.

Optimal skin

is simple.

Optimal skin

is simple.

Formulating in synergy

with skin’s biology.

Skin is a responsive, self-regulating organ—constantly adapting to environmental shifts, oxidative stress, and internal rhythms. Our formulations are developed to work in close affinity with these processes, drawing on biomimetic principles to support the skin’s natural capacity to protect, repair, and adapt over time.

Formulating in synergy

with skin’s biology.

Skin is a responsive, self-regulating organ—constantly adapting to environmental shifts, oxidative stress, and internal rhythms. Our formulations are developed to work in close affinity with these processes, drawing on biomimetic principles to support the skin’s natural capacity to protect, repair, and adapt over time.

Formulating philosophy

Formulating philosophy

Each product is developed through a process that bridges established evidence with emerging technologies—drawing from the precision of clinical insight and the evolving art of formulation. We embrace innovation not for novelty’s sake, but to create high-performance compositions that are both biologically attuned and sensorially refined.

Each product is developed through a process that bridges established evidence with emerging technologies—drawing from the precision of clinical insight and the evolving art of formulation. We embrace innovation not for novelty’s sake, but to create high-performance compositions that are both biologically attuned and sensorially refined.

Scientific validation 

Ingredients are selected based on the strength of available evidence and their relevance to skin physiology.

Precision & Purity

High-purity bioactives are used at evidence-based concentrations to ensure both performance and skin compatibility.

Biomimetic Formulation

Formulas are designed to reflect the skin’s own structures and processes, supporting long-term balance, resilience, and adaptability.

A restrained ingredient selection.

A restrained ingredient selection.

While cosmetic marketing often celebrates plant extracts as rich sources of flavonoids and other bioactive compounds, the reality is more complex. Most extracts contain only trace amounts of the molecules credited for their effects, diluted within a broad matrix of non-relevant, and often unidentified, constituents. Our approach focuses on the core activity of each formula, favouring carefully standardised extracts to deliver high-purity concentrations of biologically meaningful compounds. This ensures not only functional integrity, but also consistency and traceability across formulations.

While cosmetic marketing often celebrates plant extracts as rich sources of flavonoids and other bioactive compounds, the reality is more complex. Most extracts contain only trace amounts of the molecules credited for their effects, diluted within a broad matrix of non-relevant, and often unidentified, constituents. Our approach focuses on the core activity of each formula, favouring carefully standardised extracts to deliver high-purity concentrations of biologically meaningful compounds. This ensures not only functional integrity, but also consistency and traceability across formulations.

Rethinking molecule delivery.

Rethinking molecule delivery.

The potential of many powerful antioxidants remains untapped due to their structural instability and limited ability to penetrate the skin. When these molecules remain on the surface, even the most promising compounds show minimal biological activity. Our approach addresses this by using biomimetic liposomes engineered to carry unusually high concentrations of actives. Produced through a controlled method that ensures consistent vesicle structure and full characterization of key parameters, our delivery system enables deeper absorption and reliable performance—batch after batch.

The potential of many powerful antioxidants remains untapped due to their structural instability and limited ability to penetrate the skin. When these molecules remain on the surface, even the most promising compounds show minimal biological activity. Our approach addresses this by using biomimetic liposomes engineered to carry unusually high concentrations of actives. Produced through a controlled method that ensures consistent vesicle structure and full characterization of key parameters, our delivery system enables deeper absorption and reliable performance—batch after batch.

State-of-the Art delivery technologies.

State-of-the Art delivery technologies.

The potential of many powerful antioxidants remains untapped due to their structural instability and limited ability to penetrate the skin. When these molecules remain on the surface, even the most promising compounds show minimal biological activity. Our approach addresses this by using biomimetic liposomes engineered to carry unusually high concentrations of actives. Produced through a controlled method that ensures consistent vesicle structure and full characterization of key parameters, our delivery system enables deeper absorption and reliable performance—batch after batch.

The potential of many powerful antioxidants remains untapped due to their structural instability and limited ability to penetrate the skin. When these molecules remain on the surface, even the most promising compounds show minimal biological activity. Our approach addresses this by using biomimetic liposomes engineered to carry unusually high concentrations of actives. Produced through a controlled method that ensures consistent vesicle structure and full characterization of key parameters, our delivery system enables deeper absorption and reliable performance—batch after batch.

Enhanced Skin Deposition vs. Free Active

Encapsulation system enables up to 20x greater deposition of active compounds in the basal layers of the epidermis.

1x

1x

Results based on Franz cell diffusion testing and fluorescence confocal microscopy assessing skin delivery to the basal epidermis.

Enhanced Skin Deposition vs. Free Active

Encapsulation system enables up to 20x greater deposition of active compounds in the basal layers of the epidermis.

1x

1x

Results based on Franz cell diffusion testing and fluorescence confocal microscopy assessing skin delivery to the basal epidermis.

Principles applied

BA-Complex 01 is the first expression of our philosophy—a global serum designed to mediate and support an optimal skin state by strengthening the skin’s natural mechanisms through precision, evidence, and restraint.

BA-Complex 01

BA-Complex 01

Clinically relevant antioxidants paired with advanced delivery systems, targeting oxidative stress, skin barrier function, and visible signs of aging.

Clinically relevant antioxidants paired with advanced delivery systems, targeting oxidative stress, skin barrier function, and visible signs of aging.

BA01 is a core serum developed to support the skin’s natural defense and repair systems. It blends clinically relevant antioxidants with precision delivery to promote natural renewal processes, reinforce structural integrity, and help maintain a balanced, even-looking complexion.

Formulation

Formulation

Each active ingredient is thoughtfully selected for its biological affinity, purity, and proven efficacy, supporting the skin’s natural systems through precision and restraint.

Each active ingredient is thoughtfully selected for its biological affinity, purity, and proven efficacy, supporting the skin’s natural systems through precision and restraint.

Proprietary

BA Liposome Complex

Engineered to enhance bioactive stability, skin absorption, and targeted delivery to the lower epidermis.

Isoflavonoid (≥95%)

Astaxanthin (≥99%)

Bio-Adaptive Antioxidant Complex

A network of adaptive molecules designed to shield against environmental stressors and protect essential skin structures.

Peptide Complex

Selected peptides to support the skin’s protective mechanisms, helping to counter oxidative stress and visible inflammation through biomimetic signaling.

Formulations pipeline

Formulations pipeline

Two additional formulas are currently in development, iterated through performance testing and sensorial refinement, and shaped with precision and restraint. Each reflects our commitment to pragmatic logic, relevance, and performance, and, ultimately, a meaningful user experience.

Two additional formulas are currently in development, iterated through performance testing and sensorial refinement, and shaped with precision and restraint. Each reflects our commitment to pragmatic logic, relevance, and performance, and, ultimately, a meaningful user experience.

Formula A02

Description

Originally developed to support skin undergoing intensive retinoid use, this emulsion is designed to reinforce barrier integrity and modulate the skin’s response to irritation mediators. Through a bioadaptive approach grounded in lipid structure and compatibility, it helps restore barrier homeostasis and improve skin tolerance in sensitised or reactive conditions.

Category

Every ingredient is selected based on rigorous scientific research and proven efficacy—ensuring it delivers measurable results, not just theoretical benefits.

Status

Version 6.2 is being tested for performance and finetune feeling after drydown.

Formula A03

DESCRIPTION

A modern oil-based formulation designed to soothe and restore sensitised or impaired skin states. Delivered through a stable, skin-compatible system combining biomimetic lipids, sterols, and standardised soothing bioactives.

Category

Anhydrous formula; Skin recovery; Relipidizing care.

Status

Version 9 under evaluation for galenic texture and performance.

What's next

Stay close as this project unfolds, shaping a new approach to amplified skincare.

Stay close as this project unfolds, shaping a new approach to amplified skincare.

©2025 André Duarte

16:44

©2025 André Duarte